{"id":268797,"date":"2026-10-28T14:02:42","date_gmt":"2026-10-28T14:02:42","guid":{"rendered":"https:\/\/klak.is\/sprotar\/gleipnir-lifsmidja-dafna\/"},"modified":"2026-10-28T14:02:42","modified_gmt":"2026-10-28T14:02:42","slug":"gleipnir-lifsmidja-dafna","status":"publish","type":"sprotar","link":"https:\/\/klak.is\/en\/sprotar\/gleipnir-lifsmidja-dafna\/","title":{"rendered":"Gleipnir Life Center"},"content":{"rendered":"<p>Yfir 80% \u00feeirra pr\u00f3teina sem valda alvarlegum sj\u00fakd\u00f3mum, svo sem m\u00f6rgum tegundum krabbameina og taugahr\u00f6rnunarsj\u00fakd\u00f3ma, eru talin \u00f3l\u00e6knandi (e. undruggable) me\u00f0 hef\u00f0bundnum lyfjum. Gleipnir L\u00edfsmi\u00f0ja er l\u00edft\u00e6knifyrirt\u00e6ki sem r\u00e6\u00f0st a\u00f0 \u00feessum vanda me\u00f0 s\u00ednum einstaka SK\u00cdRNIR skimunarvettvangi. \u00cd sta\u00f0 \u00feess a\u00f0 leita a\u00f0 lyfinu sj\u00e1lfu notar SK\u00cdRNIR h\u00f6nnunarl\u00edffr\u00e6\u00f0i (e. synthetic biology) \u00ed gerfrumum til a\u00f0 svara fyrstu og mikilv\u00e6gustu spurningunni: Hva\u00f0a tv\u00f6 pr\u00f3tein \u00e1 a\u00f0 \u201el\u00edma\u201c saman til a\u00f0 gera sj\u00fakd\u00f3mspr\u00f3teini\u00f0 \u00f3virkt?<\/p>\n<p>\u00deessi n\u00e1lgun breytir lyfjaleit \u00far d\u00fdrri og handah\u00f3fskenndri leit \u00ed markvisst og kerfisbundi\u00f0 ferli. H\u00fan sparar lyfjafyrirt\u00e6kjum mikinn t\u00edma \u00ed \u00fer\u00f3unarvinnu og dregur verulega \u00far \u00e1h\u00e6ttu og kostna\u00f0i. Markmi\u00f0 Gleipnis L\u00edfsmi\u00f0ju er a\u00f0 ver\u00f0a lei\u00f0andi al\u00fej\u00f3\u00f0legur samstarfsa\u00f0ili \u00ed uppg\u00f6tvun \u00e1 n\u00fdjum me\u00f0fer\u00f0um og fl\u00fdta \u00feannig fyrir \u00fer\u00f3un svokalla\u00f0ra sameindal\u00edmslyfja (e. molecular glue drugs) gegn sj\u00fakd\u00f3mum sem hinga\u00f0 til hafa veri\u00f0 taldir \u00f3l\u00e6knandi.<\/p>","protected":false},"excerpt":{"rendered":"<p>Gleipnir L\u00edfsmi\u00f0ja er l\u00edft\u00e6knifyrirt\u00e6ki sem opnar n\u00fdjar dyr \u00ed lyfja\u00fer\u00f3un me\u00f0 byltingakenndri t\u00e6kni sem finnur lausnir gegn \u00feeim 80% sj\u00fakd\u00f3msvaldandi pr\u00f3teinum sem hinga\u00f0 til hafa veri\u00f0 talin \u00f3l\u00e6knandi (e. undruggable).<\/p>","protected":false},"featured_media":268723,"template":"","categories":[394],"tags":[],"project":[1290],"ar":[1304],"class_list":["post-268797","sprotar","type-sprotar","status-publish","has-post-thumbnail","hentry","category-dafna","project-dafna","ar-1304"],"acf":{"tengd_verkefni":[78810],"year":"2026","onepager":null,"pitch":"","eventpitch":{"eventpitch_title":"Titill \u00e1 video-i","eventpitch_videourl":"","eventpitch_date":null},"sama_teymi":null},"_links":{"self":[{"href":"https:\/\/klak.is\/en\/wp-json\/wp\/v2\/sprotar\/268797","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/klak.is\/en\/wp-json\/wp\/v2\/sprotar"}],"about":[{"href":"https:\/\/klak.is\/en\/wp-json\/wp\/v2\/types\/sprotar"}],"acf:post":[{"embeddable":true,"href":"https:\/\/klak.is\/en\/wp-json\/wp\/v2\/verkefni\/78810"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/klak.is\/en\/wp-json\/wp\/v2\/media\/268723"}],"wp:attachment":[{"href":"https:\/\/klak.is\/en\/wp-json\/wp\/v2\/media?parent=268797"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/klak.is\/en\/wp-json\/wp\/v2\/categories?post=268797"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/klak.is\/en\/wp-json\/wp\/v2\/tags?post=268797"},{"taxonomy":"project","embeddable":true,"href":"https:\/\/klak.is\/en\/wp-json\/wp\/v2\/project?post=268797"},{"taxonomy":"ar","embeddable":true,"href":"https:\/\/klak.is\/en\/wp-json\/wp\/v2\/ar?post=268797"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}